LONDON, 1590. Queen Elizabeth I's control over her kingdom is wavering. Amidst a tumultuous backdrop of Spanish plotters, Catholic heretics and foreign wars threatening the country's fragile stability, the body of a small boy is found in the City of London, with strange marks that no one can explain. When idealistic physician Nicholas Shelby finds another body displaying the same marks only days later, he becomes convinced that a killer is at work,...